The full answer
Usually, yes — it's the standard way to confirm diagnosis
Following a positive blood test, an upper endoscopy with a small intestine biopsy is the standard way doctors confirm celiac disease. During the procedure, a thin camera is passed down through the mouth to the small intestine, and tiny tissue samples are taken to check for the villi damage characteristic of celiac disease.
What it involves
The procedure is generally quick and done under sedation, and most people go home the same day. See can a biopsy miss celiac disease for what happens when results aren’t perfectly clear-cut.
Important context
Individual symptoms, reactions, medical histories, food products, and local labeling rules can vary. Community experiences are not medical evidence.
For personal medical decisions, diagnosis, testing, or treatment, consult a qualified healthcare professional.

